ERA

ERA: A Vital Step Towards Successful Conception

Endometrial Receptivity Analysis, commonly called ERA, is a specialised genetic test commonly known as an endometrial receptivity array test designed to assess the receptivity of a woman’s endometrium or womb lining. This analysis aims to pinpoint the ideal time for embryo implantation, also known as the window of implantation (WOI).

By personalising each patient’s critical period in the IVF cycle, ERA aims to optimise the chances of successful embryo implantation and subsequent pregnancy. However, like all medical procedures, ERA comes with its unique advantages, potential complications, and varied success rates. Origin Fertility specialists commonly perform the Endometrial Receptivity Array in Hyderabad to ensure the correct time for implantation.

Understanding ERA

The endometrium plays a pivotal role in conception as it is where the embryo implants and grows. The endometrium undergoes several changes throughout a woman’s menstrual cycle, reaching its peak receptivity during the window of implantation. Traditionally, this period was believed to be between days 19-21 of a regular 28-day menstrual cycle. However, this window can vary significantly among women, which is where ERA comes into play.

ERA is a genetic test that involves analysing the expression of genes associated with endometrial receptivity. The test categorises the endometrium as receptive (ready for embryo implantation), pre-receptive (not yet ready), or post-receptive (past the optimal point). By establishing a personalised WOI for each patient, ERA aims to increase the probability of successful embryo implantation. The experts at Origin Fertility Clinic & Research Centre perform effective ERA test for IVF in Hyderabad to provide the best results.

Indications for ERA

The use of ERA is particularly beneficial in some instances. These include:

1. Repeated Implantation Failure (RIF): If you have experienced multiple unsuccessful embryo transfer cycles despite transferring good-quality embryos, your doctor may recommend an ERA.

2. Unexplained Infertility: In cases where standard fertility investigations fail to identify a cause for infertility, an ERA may be conducted to assess endometrial receptivity.

3. Recurrent Pregnancy Loss (RPL): If you have experienced two or more miscarriages, your doctor may suggest an ERA to determine if the timing of embryo transfer could be a contributing factor.

The ERA Process

The process of ERA or Endometrial Receptivity Array in Hyderabad at Origin Fertility Clinic & Research Centre involves three key steps:

1. Endometrial Biopsy: This initial step involves a minor surgical procedure where a small sample of the endometrium, the lining of the uterus, is collected. The procedure is relatively quick and performed using a thin, flexible instrument called a pipelle. The pipelle is gently inserted through the cervix into the uterus to obtain a small tissue sample that contains cells from the endometrium.

2. Genetic Analysis: After the endometrial biopsy, the collected tissue sample undergoes genetic analysis in a laboratory setting. The genetic analysis may include various molecular biology methods, such as polymerase chain reaction (PCR), microarray analysis, or next-generation sequencing (NGS). By examining the expression patterns of these genes, scientists can gain insights into the receptivity of the endometrium, helping determine the optimal time for embryo implantation.

3. Personalised Embryo Transfer: Once the genetic analysis is complete and the results are obtained, your doctor will interpret the findings to determine your personalised window of implantation. This window represents the ideal timeframe during your menstrual cycle when your endometrium is most receptive to embryo implantation.

Complications of ERA

While ERA is generally safe, no medical procedure is entirely without risk. Some of the potential complications associated with ERA include:

1. Discomfort or Pain: You may experience mild discomfort during the endometrial biopsy.

2. Abnormal Bleeding: Some women may notice spotting or light bleeding after the procedure.

3. Infection: Although rare, there’s a slight infection risk following the biopsy.

4. Uterine Perforation: In extremely rare cases, the biopsy can lead to a hole in the uterus or uterine perforation.

The Success Rate of ERA

Research indicates that ERA has high sensitivity (0.99758) and specificity (0.8857) for determining endometrial receptivity status, indicating its potential to predict your personalised window of implantation (WOI) accurately.

ERA offers a promising approach for personalising fertility treatments and potentially improving IVF success rates. However, it’s crucial to remember that every individual’s fertility journey is unique, and treatment plans should always be customised to suit your specific medical needs. Before deciding, consult your doctor about the possible benefits and risks of undergoing ERA.

Why Choose Origin Fertility?

Origin Fertility is driven by a foundational belief that every person’s journey to parenthood is unique, requiring personalised medical care and treatment. Our Best Fertility Center in Hyderabad offers an extensive range of fertility treatments, including the advanced ERA. This diagnostic tool has enhanced our ability to determine the optimal time for embryo implantation. Our team of consummate professionals, headed by expert clinicians, ensures that every step of your journey to parenthood is navigated with utmost care.

We are steadfast in our commitment to uphold the highest ethical standards in treatment. Maintaining complete transparency and open communication ensures patient trust is paramount to our practice. Our comprehensive fertility treatments are evidence-based, guided by rigorous scientific research and recognised international guidelines. This dedication to ethical practices is evident in our treatments and our pricing structure, which we designed with affordability in mind.

We invite you to begin your treatment journey with Origin Fertility. Our patient-centric approach ensures you are supported through each stage of your fertility journey. Book a consultation with our team today! Together, we can explore your fertility preservation options and build a personalised treatment plan tailored to your needs.

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swathi kancha
swathi kancha
2023-08-07
We all know this journey isn’t easy, more than physical it’s an emotional ride, but I trust Rinkie mam who understands me and supports me and entire staff is with me through thick and thin. During this entire journey, I was able to develop an emotional bond with Rinkie mam and always thankful to her for helping me being strong and positive. Love the staff as well, who treat me more like a family member.
Vinod Nayak
Vinod Nayak
2023-08-05
We got to know Origin fertility clinic through online we met Dr.RINKE TIWARI she is transparent & answers all our silly questions very patiently. The doctor and the staffs were incredibly knowledgeable. The facility itself was modern, clean, and well-equipped with the latest technology. The doctors and specialists provided thorough explanations, addressing all my concerns and ensuring I felt comfortable every step of the way. They personalized my spouse treatment plan, tailoring it to my specific needs. The entire process was handled with utmost professionalism.
Dheeraj Kumar Ketireddy
Dheeraj Kumar Ketireddy
2023-08-05
Origin Fertility Center surpassed all expectations with Dr. Rinki Tiwari's exceptional expertise and compassionate care. The staff's politeness, modern facilities, and personalized treatment approach created a comfortable environment. Highly recommended for anyone seeking excellent medical attention, their dedication to patient well-being shines through in every aspect of their service. We are immensely grateful for their support throughout our journey. From the moment we stepped in, the warm and professional reception from the staff put me at ease. Dr. Tiwari's attentiveness and detailed explanations of treatment options instilled confidence in me. The clinic's clean and well-equipped facilities added to the overall positive experience. With their help, we can now proudly say that our journey has resulted in success.
Smitha Pandey
Smitha Pandey
2023-07-12
It has been an absolutely fantastic experience as we emabrk on the journey to parenthood. Dr Tiwari is extremely knowledgeable and explains each step of the process in detail in easy to understand layman's terms The staff is amazing and hospital - always greeting you with smile, everyone checks on you every now and then and is extremely helpful. They create a family bond and are amazing
Fathima
Fathima
2023-07-10
We got to know Origin fertility clinic through online and got success in our first attempt. Really thankful to her from the bottom of my heart. Dr.Rinke is transparent & answers all our silly questions very patiently. The doctor and the staffs are very compassionate and caring. The ambiance is clean and calm. Strongly recommended for all couples who are looking forward for parenthood. Thank you!
Bhaskar Behera
Bhaskar Behera
2023-07-10
I recently visited ORIGIN fertility center, headed by Dr. RINKE TIWARI and had an exceptional experience. The staffs were incredibly knowledgeable, compassionate, and attentive throughout my entire journey. The facility itself was modern, clean, and well-equipped with the latest technology. The doctors and specialists provided thorough explanations, addressing all my concerns and ensuring I felt comfortable every step of the way. They personalized my spouse treatment plan, tailoring it to my specific needs. The entire process was handled with utmost professionalism and sensitivity, and I felt supported throughout my journey.
Jamshed Alam
Jamshed Alam
2023-06-01
We visited Origin fertility clinic after 1 years of my wife's miscarriage, and concern with not able to conceive. Dr. Rinke Maa'm helped her with proper medication and by God grace, she helped my wife to able to conceive naturally even after 2 IUIs were failed. We are thankful to Rinky Maa'm and entire staffs for the continuous support. She suggests only required medications. I highly recommend her...
Srikar
Srikar
2023-04-24
We have consulted Dr. Rinky Tiwari after multiple failures as a last try. Excellent individual attention from the doctor, who does research on each and every step of the treatment and a positive atmosphere all around the hospital has helped us immensely in this journey which is successful. Unlike many other hospitals at Origin we got that customised treatment throughout journey which proved that going in a flow is not right and each patient is to be specially treated. One size does not fit all. Hence strongly recommend Origin for fertility issues.
Soujanya Kiran
Soujanya Kiran
2023-04-15
Origin fertility center is the best fertility center in Hyderabad. Needless to say Dr.Rinki madam is the best best doctor ... When we were planning for parenthood and were facing difficulty we reached out to few doctors but we were not satisfied with them. And one day we came to know about Dr.Rinki madam and since the day we met her till date she is so friendly,caring and always calm and composed and answers all our queries very patiently.I remember when first time IVF treatment failed for me , i lost hope on myself but she boosted us,motivated us and the trust we had in her made us go ahead for treatment again and bingo this time I am positive.Its because of Dr.Rinki madam we are happy and our family is happy. Words are not enough to say thank you madam .. Also the staff right from receptionist, sister, pharmacy,helping staff ,everyone are so friendly and caring. I suggest to people who are in tough time for parenthood to visit Origin fertility center, Dr.Rinki madam. Best fertility center and Best doctor .. THANK YOU ...., 🙏
asha sen
asha sen
2023-04-07
Origin Fertility Center is the best fertility center. We got success in our first attempt. Dr. Rinkie and her staff were very much available and helpful fo their patients. I would like to recommend Origin Fertility to someone who really needs help.

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